Adam Lyth was one not out, and Alastair Cook, the England captain, six not out.
Earlier, Australia were dismissed inside 37 overs after captain Michael Clarke won the toss and batted despite the overcast conditions and a green tinged pitch which promised to aid seam movement.
James Anderson took six for 47, his best innings figures against Australia, in 14.4 overs. His haul included a spell of four for seven in 10 balls after lunch.
Meanwhile fast bowler Steven Finn marked his first Test since 2013 with two for 38 in 10 overs after Durham quick Mark Wood was omitted because of ankle problems. Stuart Broad, the only other bowler used in the innings, had figures of two for 44.
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But the lively seaming pitch and overcast conditions which aided England's attack were still factors as the hosts began a reply cut short by rain.
The five-match series is level at 1-1 after England won the first Test in Cardiff by 169 runs.