The two stars, who recently teamed up for Iglesias' 'I'm a Freak', will co-headline a tour that's scheduled to take place this fall, reported Ace Showbiz.
The tour will kick off on September 12 at Prudential Center in Newark, New Jersey and will hit cities like Washington, Montreal, Toronto, New York, Kansas City, Los Angeles, Dallas and Atlanta before concluding on October 25 in Hollywood, Florida.
Colombian singer J Balvin will support the tour. Tickets will go on sale on May 9.
"Going on tour again with Enrique is exciting," Pitbull said of touring with Iglesias, in a statement.
In a separate statement, Iglesias stated, "There's no better place for me than being up on stage in front of my fans. And going on tour with a close friend and someone I admire, like Pitbull, is truly an honour. We really want to give everybody a show that they will remember for the rest of their lives.