When A-beta peptides accumulate in excessive amounts in the brain, they can form plaques, which are a hallmark of Alzheimer's disease.
Researchers from the Ohio State University found that the key to reducing A-beta peptides in laboratory mice studies was the elimination of an enzyme called jnk3.
This enzyme stimulates a protein that produces A-beta peptides, suggesting that when jnk3 activities are high, A-beta peptide production increases