The new lines are produced by companies including US giants Monsanto and DuPont, and German firms Bayer and BASF.
"All the GMOs (Genetically Modified Organisms) approved today have been proved to be safe before their placing on the EU market," the Commission said in a statement.
The ten-year authorisations will be added to the European Union's existing list of 58 GM food and feed products.
The newly authorised foods are varieties of maize, soybean, oilseed rape and cotton.
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The EU on Wednesday announced plans to allow its 28 member states to individually decide whether to allow the import of GM foods and animal feeds.
Greenpeace, the environmental group, said the new authorisations showed that European Commission chief Jean-Claude Juncker was "moving closer to the US and Monsanto" instead of its citizens.
"Earlier this week Juncker broke his promise to change rules that force GM crops onto the EU market even if a majority of countries opposes them," Greenpeace EU food policy director Franziska Achterberg said.
A huge but controversial US-EU trade deal known as the Transatlantic Trade and Investment Partnership (TTIP) is currently under negotiation by both sides.