Her visit on Wednesday and Thursday, which comes just days after Netanyahu started a new term as Israeli premier, will be "to discuss the bilateral relations as well as prospects for the Middle East Peace Process," her office said.
The former Italian foreign minister will also meet a number of other Israeli and Palestinian officials, the statement from her office said without giving further details or the exact venue of the talks.
She has been criticised in Israel for her vocal insistence that a two-state solution is the only way forward and for her condemnation of Israeli settlement-building.