The 65-year-old saw his high-flying career at the head of the International Monetary Fund and presidential prospects implode when a chambermaid at a New York hotel accused him of sexual assault in 2011.
While those criminal charges were dropped and the case settled in a civil suit, DSK, as he is known in France, faced further humiliation when sordid details emerged of his participation in orgies with prostitutes.
Strauss-Kahn, who denies the charge, was ordered to stand trial in 2012 by investigating magistrates despite prosecutors calling for the charges to be dropped for lack of evidence.
The case, known as the "Carlton Affair", began with a probe of a notorious pimp who owns a string of bordellos near the French border in Belgium, where prostitution and brothel ownership are legal.
More From This Section
Strauss-Kahn's name cropped up when one of the prostitutes working for the "Carlton" ring told investigators she had been paid to participate in a sex party in a luxury Parisian hotel attended by the former head of the IMF, prosecution sources said.
Subsequent investigations revealed DSK had taken part in such parties in Belgium, Paris and even on business trips to Washington, according to the sources, who wished to remain anonymous.
He is one of 14 defendants in the trial which is expected to last three weeks. He is scheduled to take the stand himself from February 10.