After arriving at the airport here from Madurai, she left for Singapore by an Indigo flight, airport officials said.
Earlier, the Madurai Bench of the Madras High Court had reserved its order on the anticipatory bail petition moved by her in connection with a sexual harassment case filed by her two domestic aides.
On August 26, the Supreme Court had granted protection from arrest to Sasikala Pushpa for six weeks in the case.
The Delhi High Court had on August 11 asked Tamil Nadu government not to take any coercive action till August 22 against the expelled AIADMK MP, her husband and their son who are facing the harassment case.