"Decisions, investment, legislation and a high degree of commitment by the authorities and regulatory bodies of Panama" are needed to keep Panama off lists that would punish it as a designated tax or money-laundering haven, the report by the government-appointed international Committee of Independent Experts said.
Automatic sharing of tax information and holding lawyers to higher standards were among its key recommendations.
The panel was established by Panamanian President Juan Carlos Varela in April, days after the "Panama Papers" revelations that showed how a law firm in the Central American nation set up companies to help the world's wealthy shield their assets from scrutiny.
It was seen as an effort by Varela to limit the damage from the scandal, which sparked tax probes in several countries around the world, protests that led to the resignation of Iceland's prime minister, and prompted France to put Panama back on its blacklist of uncooperative tax havens.
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The seven-member Committee of Independent Experts was initially headed by Nobel-winning US economist Joseph Stiglitz. But he and a Swiss anti-corruption expert, Mark Pieth, resigned in August, saying Varela's government was curbing their independence in making the panel's findings public.
They released their own report which called on the United States and Europe to lead a global fight against financial centres seen to be lax in cracking down on financial corruption and tax dodging.
Varela last week warned France of "diplomatic measures" from January 2017 if it kept Panama on its blacklist. Panama's parliament has already approved a law that, if approved by Varela, would impose tax and migratory penalties on France.
European Union finances ministers in early November met to discuss drawing up a list of countries deemed to be uncooperative in sharing tax information.