Protesters stopped vehicles carrying fruits, vegetables and food grains and emptied milk containers on roads.
"We gave call for protest through the social media which has evoked a good response from farmers. Prices of food grains have nosedived and farmers are not even recovering the money they invested," MP Kisan Sena secretary Jagdish Rawalia told PTI.
Farmers in Indore, Ujjain, Dewas, Jhabua, Neemuch and Mandsaur districts are supporting the protest, he said.
Madhya Pradesh finance minister Jayant Malaiya sought to downplay extent of the protest.
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"Only a handful of farmers were protesting and there was no report of shortage of food grains, milk, fruits and vegetables in any part of the state," he said.
"We are ready for talks with farmers," he added.
Farmers in the state are happy, and MP has bagged five consecutive awards set up by the Centre for food production, the minister said.
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