Until now, researchers believed farming was "invented" some 12,000 years ago in the Cradle of Civilisation - Iraq, the Levant, parts of Turkey and Iran - an area that was home to some of the earliest known human civilisations.
The new study by an international collaboration of researchers from Tel Aviv University, Harvard University, Bar-Ilan University, and the University of Haifa offers the first evidence that trial plant cultivation began far earlier - some 23,000 years ago.
"While full-scale agriculture did not develop until much later, our study shows that trial cultivation began far earlier than previously believed, and gives us reason to rethink our ancestors' capabilities," said Professor Marcelo Sternberg from TAU's Faculty of Life Sciences.
"Those early ancestors were more clever and more skilled than we knew," said Sternberg.
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Although weeds are considered a threat or nuisance in farming, their presence at the site of the Ohalo II people's camp showed the earliest signs of trial plant cultivation - some 11 millennia earlier than conventional ideas about the onset of agriculture.
The site was unusually well preserved, having been charred, covered by lake sediment, and sealed in low-oxygen conditions - ideal for the preservation of plant material.
Researchers examined the weed species for morphological signs of domestic-type cereals and harvesting tools, although their very presence is evidence itself of early farming.
"This uniquely preserved site is one of the best archaeological examples worldwide of the hunter-gatherers' way of life," said Sternberg.
"Because weeds thrive in cultivated fields and disturbed soils, a significant presence of weeds in archaeobotanical assemblages retrieved from Neolithic sites and settlements of later age is widely considered an indicator of systematic cultivation," according to the study.
Upon retrieving and examining approximately 150,000 plant specimens, the researchers determined that early humans there had gathered over 140 species of plants.
These included 13 known weeds mixed with edible cereals, such as wild emmer, wild barley, and wild oats.
The researchers found a grinding slab - a stone tool with which cereal starch granules were extracted - as well as a distribution of seeds around this tool, reflecting that the cereal grains were processed for consumption.
The study was published in the journal PLOS ONE.