Hassakeh province which borders Turkey and Iraq has become the latest battleground for the fight against IS. It is predominantly Kurdish but also has populations of Arabs and predominantly Christian Assyrians and Armenians.
In pre-dawn attacks, the group on Monday attacked communities nestled along the Khabur River, seizing dozens of people, many of them women and children. Thousands of others fled to safer areas.
The fate of those kidnapped, almost all of them Assyrian Christians, remained unclear today two days after they were seized. The abduction added to fears among religious minorities in both Syria and Iraq, who have been repeatedly targeted by the Islamic State group.
"We are watching a living history and all that comprises disappear," wrote Mardean Isaac of A Demand for Action, an activist group that focuses on religious minorities in the Middle East.
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He called for further airstrikes by American and western powers to assist those Assyrian and Kurdish forces fighting the militants in Syria. The United States and coalition of regional partners are conducting a campaign of airstrikes against the group.
In its first comments on the subject, the Syrian state-run news agency SANA said around 90 civilians had been kidnapped by IS. It said that the militants burned people's homes and stole their properties, adding that those kidnapped were taken to Shaddadi city.
The Islamic State group has a history of killing captives, including foreign journalists, Syrian soldiers and Kurdish militiamen. Most recently, militants in Libya affiliated with the extremist group released a video showing the beheading of 21 Egyptian Christians.
The extremists could also use the Assyrian captives to try to arrange a prisoner swap with the Kurdish militias it is battling in northeastern Syria.