Singh, 70, died late last night.
"He complained of chest pain when he reached the Lal Bahadur Shastri Airport to board a flight for Delhi. He was taken to the Banaras Hindu University (BHU) Trauma Centre from there but he could not be saved," O P Upadhyaya, chief medical superintendent of the Sunder Lal hospital in the BHU, said.
Singh, the 25th vice chancellor of the BHU, hailed from neighbouring Jaunpur district's Kalvari village.
Uttar Pradesh Chief Minister Yogi Adityanath condoled Singh's death.
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"Lalji Singh was the father of DNA finger printing. The country has lost a great educationist and scientist after his death," he said.
Singh was also the recipient of the prestigious Padma Shri award.
He joined the BHU in 1962 after completing his intermediate from a school in his native district.
Singh, the founder of the Centre for Cellular and Molecular Biology (CCMB), also served asits director.
He was the officer-on-special-duty (OSD) at the Centre for DNA Finger Printingand Diagnostics (CDFD) in Hyderabad between 1995-1999.