Hundreds of homes and businesses have been swallowed by the frigid, muddy waters. Scores of people have had to be rescued by boat -- including one man plucked from the roof of his home as it floated away.
Governor Jay Nixon pleaded with people to heed evacuation orders and stay off flooded roadways, after the body of a motorist who was swept off a road was recovered on yesterday.
"This historic flooding event will continue to cause significant hazards and disruptions -- from Missourians being forced from their homes, to businesses temporarily closing, to traffic congestion and impacts on interstate commerce due to the closure of a major trucking corridor," Nixon said in a statement.
"I thank the many Missourians who are assisting their neighbors by providing rooms in their homes, helping with sandbagging efforts and countless other acts of kindness."
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The recovery will be long and costly, local officials feared.
The mayor of hard-hit Fenton, Missouri watched in horror as a house swept away by the floods struck a newly-built bridge.
"It was kind of our pride of a new bridge being built. And you see that house hit it, was very nerve wracking," Michael Polizzi told CNN.
The flooding has been so widespread he doesn't even know whose home it was that struck the bridge. Thankfully, nobody has been reported missing so far from his suburban St. Louis town.
President Barack Obama called Nixon from Hawaii, where he is on vacation, to offer federal assistance if it is needed.