Mnangagwa served for decades as Mugabe's enforcer, a role that gave him a reputation for being astute, ruthless and effective at manipulating the levers of power.
Among the population, he is more feared than popular, but he has strategically fostered a loyal support base within the military and security forces.
A leading government figure since Zimbabwe's independence in 1980, he became vice president in 2014 and is so widely known as the "Crocodile" that his supporters are called Team Lacoste for the brand's crocodile logo.
Mugabe unwittingly set in motion the events that led to his own downfall, firing his vice president on November 6.
Also Read
Mnangagwa fled the country to avoid arrest while issuing a ringing statement saying he would return to lead Zimbabwe.
"Let us bury our differences and rebuild a new and prosperous Zimbabwe, a country that is tolerant to divergent views, a country that respects opinions of others, a country that does note isolate itself from the rest of the world because of one stubborn individual who believes he is entitled to rule this country until death," he said in the November 8 statement.
For weeks, Mnangagwa had been publicly demonized by Mugabe and his wife. Grace, so he had time to prepare his strategy. Within days of the vice president's dismissal, his supporters in the military put Mugabe and his wife under house arrest.
When Mugabe refused to resign, a massive demonstration Saturday brought thousands of people into the streets of the capital, Harare. It was not a spontaneous uprising. Thousands of professionally produced posters praising Mnangagwa and the military had been printed ahead of time.
At the same time, Mnangagwa's allies in the ruling ZANU- PF party lobbied for the removal of Mugabe as the party leader.
At a Central Committee meeting on Sunday, Mnangagwa was voted in as the new leader of the party, which had been led by Mugabe since 1977.
In an interview with The Associated Press years ago, Mnangagwa was terse and stone-faced, backing up his reputation for saying little but acting decisively. Party insiders say that he can be charming and has friends of all colours.
Disclaimer: No Business Standard Journalist was involved in creation of this content