The symphony's two conductors show how difficult that can be, but also how satisfying success is.
One of them, Negin Khpolwak, was supported by her father when she joined the Afghanistan National Institute of Music and then became part of its girls' orchestra, called Zohra. But the rest of her family was deeply against it. Her uncles cut off ties with her father.
"They told him he is not their brother anymore," said Khpolwak, now 20. "Even my grand-mother disowned my father."
Her father sent her to the orphanage because he was afraid for her safety in their home province of Kunar in eastern Afghanistan, an area where Taliban militants are active.
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The institute is one of the only schools in Afghanistan where girls and boys share classrooms, and it draws its students from the ranks of orphanages and street children, giving them a chance at a new life. Khpolwak studied piano and drums before becoming the orchestra's conductor.
More than 30 girls aged 12 to 20 play in Zohra, which is named after a goddess of music in Persian literature.
"The formation of the orchestra is aimed at sending a positive message to the community, to send a positive message to the girls, to encourage families and girls to join the music scene of the country," said Ahmad Naser Sarmast, the institute's founder and director.
Sarmast has experienced firsthand the militants' hatred of music. In 2014, a Taliban suicide bomber blew himself up at a concert Sarmast was attending. He was wounded and a German man in the audience died.
Since then, Meena has disappeared. Last year, the 7th grader told the school she had to attend her sister's wedding in her family's village in eastern Nangarhar province.
She never returned, a sign of how tenuous people's situation is in a country where war rages, communications are poor and poverty is rife. Sarmast said the school has not been in contact with her, but he's hopeful she'll return to the school and Zohra.
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