AFP Sports selects five of the best Madrid derbies of all time between the first two sides ever to compete a Champions League final from the same city:
Real Madrid 2 Atletico Madrid 1, European Cup semi-final, May 13, 1959
Three matches were needed to decide the first meeting between the sides in European competition in the semi-finals of the European Cup in 1959.
Real won the first leg 2-1 at the Santiago Bernabeu before Atletico levelled the tie two weeks later with a 1-0 victory.
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Real Madrid 1 Atletico Madrid 3, La Liga, October 30, 1999
In what was to become the worst season in Atletico's history as they were relegated from the top flight, there was one moment of glory for Los Rojiblancos as one of just nine league victories that season came at the Bernabeu thanks to two goals from Jimmy Floyd Hasselbaink and another from Jose Mari after Fernando Morientes' opener for Real.
It took another 14 years and 25 derbies for Atletico to taste victory over Real, but they ended that painful run in style by winning the Copa del Rey on Real's patch at the Bernabeu.
Atletico were forced to come from behind as Cristiano Ronaldo headed Real in front, but Diego Costa quickly levelled and Miranda handed Atletico a 10th Cup win when he glanced home Koke's cross in extra time.
Real Madrid 4 Atletico Madrid 1 (after extra-time), Champions League final, May 24, 2014
Real then ran riot in extra-time with Gareth Bale, Marcelo and Cristiano Ronaldo all netting to deliver Los Blancos' long-awaited 10th European Cup.
Real Madrid 1 Atletico Madrid 0, Champions League quarter-final, second leg, April 22, 2015
Less than a year on from the Lisbon final, Real got the upper hand in Europe once more as they snapped a seven-game winless streak against Atletico thanks to Javier Hernandez's goal a minute from time to seal a 1-0 aggregate win after Arda Turan's red card had left Atletico down to 10 men.