A large number of devotees had gathered at the temple, located around 60km from here, for Durga Puja festivities today.
The stampede apparently occurred after police resorted to a mild lathicharge to control the crowd of devotees moving towards the shrine, they said.
As the stampede occurred, over 100 people ran towards a bridge across Sindh river. Some of the devotees are feared to have fallen into the river and are untraceable so far, police said.