The three-storey residential structure, which was nearly 80-year-old, caved in yesterday in Subhashganj area of Dabra tehsil in Gwalior district.
A labourer was engaged in some repair work on the ground floor when the building came crashing down, they said.
The deceased were identified as building owner Dinesh Vishwari (45), his wife Mamta (40), daughter Ritika (12), Mahinder Kaur (said to be a tenant) and Laxman, the labourer.
Monika (20), the other daughter of Vishwari, suffered injuries and has been admitted to a local hospital, police added.