The Emiratis were among 13 people killed when explosives hidden in a sofa detonated inside the governor's compound in southern Kandahar yesterday, while the UAE's ambassador to Afghanistan escaped the attack with injuries.
Just hours before, twin Taliban blasts in Kabul tore through employees exiting a parliament annexe, which houses the offices of lawmakers, killing at least 36 people and wounding 80 others.
And earlier yesterday, a Taliban suicide bomber killed seven people in Lashkar Gah, the capital of volatile Helmand province, as the militants ramp up nationwide attacks despite the onset of winter, when fighting usually wanes.
Kandahar's governor Humayun Azizi and UAE envoy Juma Mohammed Abdullah Al Kaabi were wounded by flames from the explosion, but many others were burned beyond recognition, said provincial police chief Abdul Raziq, who was at the scene when the blast occurred.
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The Emirati officials killed were "on a mission to carry out humanitarian, educational and development projects", the UAE's official WAM news agency said on Wednesday.
"This incident will in no way affect the relations and cooperation between Afghanistan and UAE," President Ashraf Ghani said, ordering an investigation into the bombing.
In the first explosion, a suicide bomber blew himself up next to a minibus transporting government employees. As rescuers reached the scene, a car bomb exploded.
Among the 36 dead were four policemen who were killed in the second explosion when they rushed to help the victims of the first blast.
Health ministry spokesman Waheed Majroh warned that the toll was expected to rise as many of the wounded were battling for their lives in hospital.
Condemning the "barbaric attack", Ghani lashed out at the Taliban for the assault on civilians, which left the area littered with bloodied bodies.
Yesterday's carnage came just ten days before Donald Trump is sworn in as US president.