Malaysia Airlines flight MH17 "broke up in the air probably as the result of structural damage caused by a large number of high-energy objects that penetrated the aircraft from outside," said a highly anticipated report by the Dutch Safety Board.
The findings appear to back up claims that the Boeing 777, which crashed in July as it was flying from Amsterdam to Kuala Lumpur, was hit by shrapnel from a missile.
Kiev and the West have accused pro-Russian separatists of shooting down the plane with a surface-to-air BUK missile supplied by Moscow.
But Russia, which denies mounting Western claims of direct involvement in the five-month conflict in Ukraine, blamed government forces for the attack.
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The MH17 disaster was the second tragedy for Malaysia Airlines after the mysterious disappearance of flight MH370 in March, and threw the global spotlight back on the bloody uprising in eastern Ukraine.
The majority of people on board were Dutch citizens.
Dutch investigators have been unable to visit the rebel-controlled site in the Donetsk region because of the fighting, and have relied on information from Ukrainian crash specialists for information from the scene.
The findings are based on information from the aircraft's black boxes, and pictures and video taken at the scene, as well as information supplied by Ukranian air traffic control.
The Dutch Safety Board the OVV said a full report is not expected until until mid-2015.
So far only 193 victims of flight MH17 have been identified.
Air crash investigators hope they may be able to return to the crash site if a ceasefire agreed on Friday between the Ukraine government and the separatist rebels holds.
Kiev has accused the insurgents of repeated violations of the tenuous truce, and today the government said four soldiers had been killed and 29 wounded since Friday.
It also reported that the government-controlled airport outside the main insurgent stronghold of Donetsk was hit by rocket and mortar fire overnight.