The match, which is expected to set the tone for a gruelling season ahead, promises to be an exciting face-off at the SCA Stadium, with Australia keen to test their young players before the return Ashes showdown with England.
The elements, though, could play spoilsport. The state has been experiencing heavy downpour and the Met department has forecast more rains till tomorrow.
The two teams have faced off in seven previous T20 games, with Australia holding a slightly better record at 4-3.
India last played a T20 match against Pakistan at Ahmedabad in December.
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After a two-month break from international cricket, skipper Mahendra Singh Dhoni will look to re-start his stint at the helm with a win. He had warmed up nicely with a good outing for Chennai Super Kings in the CLT20.
The 31-year-old had also scored a quick-fire 52 off 35 balls against the West Indies A in a T20 game in Bangalore.
Apart from his explosive batting, Yuvraj's left-arm spin will also be handy in the shortest form of the game.