Doctors at Houston Methodist Hospital decided to let the 88-year-old wife of former President George H W Bush go home yesterday morning, after "a couple truly great days" that family spokesman Jim McGrath said left her eager to leave.
Bush was hospitalised on Monday for what was initially described as "a respiratory-related issue" but later confirmed to be pneumonia.
McGrath downplayed the condition, noting it was "caught early." He said on Friday that doctors were pleased at Bush's response to treatment and were discussing post-hospitalisation medication scenarios, Houston Chronicle reported.
After being admitted, she received public messages of support, besides wishes from US President Barack Obama and former president Bill Clinton.
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"I cannot thank the doctors and nurses at Houston Methodist enough for making sure I got the best treatment and got back to George and our dogs as quickly as possible," the former first lady said in a statement yesterday.
Bush was visited at the hospital by son Neil and daughter Dorothy Bush Koch in addition to her husband, the report said.
Her discharge from the hospital will allow the Bushes to celebrate their 69th wedding anniversary at home tomorrow. They are the nation's longest-married former first couple.