The youths were travelling in two motorcycles when the Bolangir-bound bus hit them last night, Aska police station inspector-in-charge Baleswara Gidhi said.
The driver of the bus fled after the accident.
While one deceased was yet to be identified, the other three were identified as Digambara Pradhan (25), his brother Dillip (20) of Dasamunduli village and Maheswara Rout (25) of Bada Pankalabai village, Gidhi said.
Angry family members of the deceased staged a dharna at Aska today demanding compensation and arrest of the driver of the killer bus immediately.