The blast occurred in the morning at the Jinshan Chemical Plant Co Ltd in an economic development zone in Linshu County while maintenance work was underway, according to the county government.
Four people were killed and six others wounded in the blast, local authorities said, adding that two persons were severely injured.
Owner of the chemical plant is in police custody, state- run Xinhua news agency reported.
Two persons were killed and eight others injured in a chemical factory blast in China's northwestern Xinjiang Uygur Autonomous Region last year.
Disclaimer: No Business Standard Journalist was involved in creation of this content