"After Patrick Modiano, another Frenchman reaches the top: congratulations to Jean Tirole," Valls wrote on Twitter after the Nobel economics prize was announced, adding it "really thumbed the nose at French bashing."
Modiano's win for literature last week was already seen as a boost for a nation in the doldrums with a stagnating economy and deeply unpopular government.
Valls hashtagged his twitter remark #fiersdelafrance ("Proud of France"), after previously hitting out at the gleeful crowing of newspapers and businessmen over the morose state of the nation.
On a trip to London earlier this month, Valls slammed the "bias, prejudices and attacks" on France in the British press.