A wing fragment found on the island last month was the first solid evidence of the fate of the plane that disappeared March 8, 2014, with 239 people aboard.
Malaysian authorities say the piece is part of the plane, though French, US and Australian authorities haven't definitively identified it.
Over the past 10 days, searchers scoured nearly 10,360 square kilometers of ocean using a plane, helicopters and a ship, but found "nothing suspected of having any connection to a plane," local authorities said in a statement.
Searchers will now adopt a "watchful vigilance posture" while engaged in other missions in the search zone, authorities said.
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Nearly 200 police officers on foot patrols also searched nearly the entire east coast of the island for signs of the missing Boeing 777. Several objects have already been sent for further examination.
Last week, a local environmental group found a large piece of metal debris on the beach and handed it over to gendarmes for further inspection.