Macron made the announcement a day after Weinstein was expelled by the Academy of Motion Picture Arts and Sciences.
In an interview with French TV channel TF1, Macron confirmed he had reached out to the Grand Chancellor of the Order in Paris to ask the institution to revoke Weinstein's Legion of Honor, France's highest award.
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Then-president Nicolas Sarkozy had given the Legion of Honor to Weinstein in 2012, after "The Artist", which Weinstein distributed and campaigned for, won five Oscars.
"I have asked the Grand Chancellor of the Order to examine quickly this case and launch a disciplinary procedure (against Weinstein)... considering the gravity of the facts," said Macron, adding that the Chancellor will have to make the ultimate decision.
Earlier this week, the Grand Chancellor of the Order told Variety that it would not consider stripping Weinstein of the decoration until there is a "final condemnation."
Macron, however, is looking to fast-track the process as he argued Weinstein violated the code of ethics of the Legion of Honor by behaving "in a way that's contrary to honor.