Pep Guardiola takes reigning champions Manchester City to struggling Huddersfield on Sunday, with the Premier League's bottom side facing the prospect of finding themselves on the receiving end of Kevin De Bruyne's frustration.
Arguably City's standout performer in their record-breaking title campaign last season, the Belgian's season has been badly interrupted by two lengthy spells on the sidelines with knee problems.
Now fully fit, De Bruyne has cut a frustrated figure on occasion, most notably when substituted during his team's emphatic 9-0 victory over League One Burton in the semi-final of the League Cup last week.
De Bruyne ran down the tunnel after being replaced in that game and, according to reports, watched the final exchanges from the City dressing room rather than from the bench, as club protocol dictates.
Coincidence or not, De Bruyne found himself left out of the starting line-up for City's next game, the 3-0 victory over Wolverhampton on Monday, although the fact he was joined there by frontline players such as Sergio Aguero, Riyad Mahrez and Ilkay Gundogan also spoke volumes about the club's strength in depth.
Guardiola has talked about how De Bruyne needs to get game-time under his belt to rediscover the form that made him one of the Premier League's star players and a potentially testing match against an in-form Wolves team seemed a perfect scenario for him.
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Guardiola declined to go into specifics about De Bruyne's reaction to being substituted against Burton, pointing out, instead, that the squad's depth presented him with numerous problems.
Young playmaker Phil Foden, for example, might have expected more minutes given De Bruyne's extended absences this season, but he did not even make the bench for the Wolves game and has yet to start a league game in his career.
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"It is what it is. One of my favourite players, Phil, was not in the 18 but there are a lot of games. When they come in they need to play good because if they don't another one is going to play. I'm unfair on many players. It is what it is."