Timur Bekmambetov is directing the movie, which is both a remake of the Charlton Heston-starring 1959 movie that won 11 Oscars and an adaptation of the Lew Wallace novel 'Ben-Hur: A Tale of the Christ', published in 1880.
If the talks come through, Gadot will play Esther, a slave with whom Ben-Hur falls in love, said the Hollywood Reporter.
The script for the Paramount and MGM's retelling of old classic was written by Keith Clarke with a rewrite by John Ridley, said the Hollywood Reporter.
The film will shoot in Europe early next year and is eyeing a February 2016 release date.
Gadot will play the role of Wonder Woman in the upcoming 'Batman v Superman: Dawn of Justice'.