Nikshep is third big casualty of the tournament so far as top seed IB Akshay and third seed Sachin Kumar have already been knocked out.
Vishu had an easy outing against Vikrant Dahiya, scoring a 6-2 6-1 win while Punjab boy Fatehdeep edged past Paramveer Singh Bajwa 6-4 7-5.
In the other boys under-16 matches of the day, Prajwal Dev blanked Aryan Goves 6-0 6-0 while Udayan Bhakar rallied to go past Alex Solanki 3-6 6-3 6-3.
M Sai Nikhil, Shashank Nautiyal and Bijay Gyan Bhaskar completed the quarter-final line-up in the category.
In the girls under-16, top seed S Snehadevi looked in trouble after she lost the opening set but then got things under control to make it to the quarter-finals with a 2-6 6-4 6-1 win over Sai Avanthika.
Second seed Pranjala Yadapalli, who last week won the Girls under 18 title, entered the quarterfinals by beating Mihika Yadav 6-3 6-4.
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Fourth seed Akshara Iska beat Thanushree Palani Vale 6-3 5-7 6-1, while Himani Mor, seeded fifth, defeated A Shameena 1-6, 7-5, 6-0.
Devanshi Bhimjiyani, Vanshika Sawhney, Nayanika Devi and Ramya Natraj were the other seeded player who made it to the quarter-finals without any problem today.
In the boys under-14, top seed BR Nikshep made up for his loss in the under-16 category with a 6-0 6-1 victory over Mingkhi Talom.
Second seed Nitin Kumar Sinha went past Yash Yadav 6-3, 1-6, 7-6(2). Also making it to the next round were Paramveer Singh Bajwa, Amarnath Arora, Alex Solanki, Udayan Bhakar,Sanil Jagtiani and P V Gnana Bhask.