According to his manager and booking agent, Carrie Moore-Reed, Lindsey passed away at a healthcare centre in Nashville after a brief illness, reported Aceshowbiz.
Two of Lindsey's former co-stars, Andy Griffith and Ron Howard, expressed their grief over the loss.
"George Lindsey was my friend. I had great respect for his talent and his human spirit. In recent years, we spoke often by telephone," said 85-year-old Griffith.
"Our last conversation was a few days ago ... I am happy to say that as we found ourselves in our eighties, we were not afraid to say, 'I love you.' That was the last thing George and I had to say to each other," he added.
"George Lindsey-warm intelligent lovable He generated lots of laughs & raised a lot of money for Special Olympics RIP George," Howard tweeted.
Lindsey is survived by son George Lindsey Jr and daughter Camden Jo Lindsey Gardner.