Second-seed Ghosal breezed past Singapore's Benedict Chan 11-2, 11-3, 11-5 to join compatriots Vikram Malhotra (10th seed), Mahesh Mangaonkar (11th seed), Harinder Pal Sandhu (15th-seed) and Velavan Senthilkumar in the third round.
Mangaonkar beat Vivian Rhamanan of Singapore 11-4, 11-7, 11-6, while Malhotra defeated Alireza Shameli of Iran 11-7, 11-8, 15-13 in another match.
Earlier, Senthilkumar, who had reached two PSA World Tour event finals recently, brushed aside Soheil Shameli of Iran 11-1, 11-5, 11-5 in the first round and received a walk over from Farhan Zaman of Pakistan.
In the women's section, Indian player Sunayna Kuruvilla stunned 12th-seed Choe Yura of Korea in straight games. However, R Lakshya was outlasted by 11th seed Foo Zoe Yuk Han of Malaysia in five games.
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In another match, ninth-seeded Indian Sachika Ingale lost a five-game encounter to Malaysia's Aifa Zaman.
Top-seed Max Lee of Hong Kong, meanwhile, outplayed Navid Maleksabet of Iran 11-8, 11-6, 11-6 to sail into the pre- quarterfinals.
Results: Men's singles (second round): Max Lee (1) (Hong Kong) beat Navid Maleksabet (Iran) 11-8, 11-6, 11-6; Wong Chi Him (13) (Hong Kong) beat Samuel Kang (Singapore) 11-4, 12-10, 11-7; Abdulla Al-Tamimi (6) (Qatar) beat Waqar Mehboob (Pakistan) walkover; Yuen Chee Wern (7) (Malaysia) beat Ko Young-Jo (Korea) 11-8, 11-9, 11-7; Ahmad Alsaraj (Jordan) beat Tayyab Aslam (12) (Pakistan) walkover.
Harinder Pal Singh Sandhu (15) (India) beat Reymark Begornia (the Philippines) 11-1, 11-5, 11-4; Velavan Senthilkumar (India) beat Farhan Zaman (9) (Pakistan) walkover; Mohd Nafiizwan (3)(Malaysia) beat Aditya Jagtap (India) 11-5, 11-6, 11-8.
1st round: Navid Maleksabet (Iran) beat Robert Garcia (the Philippines) 6-11, 11-6, 11-9, 7-11, 11-6; Samuel Kang (Singapore) beat Arhant Keshar Simha (Nepal) 11-4, 11-1, 11-2; Reymark Begornia (the Philippines) beat Erfan Jamshidi (Iran) 11-4, 11-5, 11-3; Velavan Senthilkumar (India) beat Soheil Shameli (Iran) 11-1, 11-5, 11-5; Aditya Jagtap (India) beat Ryunosuke Tsukue (Japan) 9-11, 7-11, 11-6, 11-6, 11-4.
Women's singles (1st round): Lee Jihyun (Korea) beat Taba Taghavi (14) (Iran) 9-11, 11-5, 11-6, 11-5; Rachel Mae Arnold (8) (Malaysia) beat Park Eunok (Korea) 11-8, 11-8, 11-6; Liu Tsz Ling (5) (Hong Kong) beat Au Yeong Wai Yhann (Singapore) 11-9, 11-7, 11-5; Eum Hwayeong (Korea) beat Ailee Nayeri (15) (Iran) 4-11, 4-11, 11-3, 11-6, 11-6; Lee Andrea Jia Qi (10) (Malaysia) beat Fereshteh Eghtedari (Iran) 11-5, 11-3, 11-4.
Satomi Watanabe (16) (Japan) beat Urwashi Joshi (India) 11-5, 12-10, 11-3; Foo Zoe Yuk Han (11) (Malaysia) beat R Lakshya (India) 9-11, 11-4, 9-11, 11-6; Sunayna Kuruvilla (India) beat Choe Yura (12) (Kor) 11-4, 11-8, 11-8; Aifa Zaman (Malaysia) beat Sachika Ingale (India) 11-7, 11-6, 7-11, 11- 13, 13-11.