Krishnapatnam is a privately built all-weather, deep-water port in Nellore district of Andhra Pradesh.
The notification said international travellers henceforth can use the port for entry into and exit from India with valid travel documents for all classes of passengers.
The notification was issued as per the Passport (Entry into India) Rules, 1950.
The move is expected to boost cruise ships travelling to Andhra Pradesh, a home ministry official said.
Krishnapatnam is also expected to becoming the largest automated port for exports and imports in South Asia.