In a statement, Al-Azhar, Egypt's highest Sunni institution, said Tayeb had reversed his previous decision to meet Pence, who is due to travel to Egypt and Israel in the second half of December.
Tayeb announced "his categorical rejection of a formal request from US Vice President Mike Pence to meet with him on December 20", Al-Azhar said.
The US embassy had submitted an official request a week ago, "and the grand imam had agreed to this, but after the unjust and unfair American decision on Jerusalem, Al-Azhar's grand imam announces his strong and decisive rejection of this meeting".