Teenager Mason Greenwood again grabbed his chances for Manchester United, scoring twice in a 4-0 thrashing of AZ Alkmaar in the Europa League.
Earlier Arsenal came back from 2-0 down to draw 2-2 at Standard Liege on Thursday and also make sure of a place in the last 32 as Group F winners.
With Wolves, who crushed Besiktas 4-0, also advancing, English clubs ended with a full house in Europe with the three Europa League entries following the Premier League's four Champions League teams into the knockout rounds.
Spanish clubs also completed a full set when Getafe joined already-qualified Sevilla and Espanyol by scoring three times in the last 14 minutes to beat Krasnodar 3-0 in a showdown for second place in Group C.
However, Bundesliga leaders Borussia Moenchengladbach and Italian power Lazio made surprising exits.
At Old Trafford, in a battle for top spot in Group L, Alkmaar matched a youthful United side until the 53rd minute when veteran Ashley Young smashed the home team ahead.
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Greenwood pounced on a loose ball to snap the second into the corner of the net. After Greenwood was fouled, Juan Mata converted a penalty.
Then the Spaniard set up Greenwood for another crisp low left-footer inside the post.
"Mason's a different class as a finisher," said United boss Ole Gunnar Solskjaer.
"If there's anything around the box you expect him to get a shot off and on target, he's good at creating space for himself and right-foot, left-foot it doesn't matter."
- Late drama -
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