Earnings after tax rallied 20.8 percent to USD 8.846 billion in 2013, compared with the previous year, GSK said in a results statement.
Turnover advanced one percent to 26.5 billion, but revenue from sales of drugs in China plunged 18 percent, hit by Beijing's probe into bribery allegedly carried out by senior GSK staff.
Excluding China, emerging markets sales grew by five percent. US sales expanded by one percent, while Europe was flat.
"The group takes these allegations seriously and is continuing to cooperate fully with the Chinese authorities in this investigation."
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GSK added that it was unable to provide the market with a reliable estimate of any potential financial fallout.
Last July, GSK admitted that senior employees at its China division appeared to have breached Chinese law, after authorities alleged that employees had bribed government officials, pharmaceutical industry groups, hospitals and doctors to promote sales.
"GSK's trading performance in 2013 was in line with our guidance, despite some unexpected challenges and reflected the improving balance of our sales base," Witty said in the earnings release.