"Masked assailants fired at the patrol from a private car," Ismailia's security director was quoted as saying by Ahram Online.
The attack took place north of the city, where suspected militants have repeatedly targeted security forces in recent weeks, the officials said.
More than 100 policemen have been killed across Egypt in attacks and clashes, especially since the military toppled Islamist president Mohammed Morsi on July 3.
In a separate incident, unidentified assailants attacked the main satellite centre with a rocket propelled grenade today in Cairo.