The annual two-weekend music festival out of Indio, California, announced its official lineup on Monday, said The Hollywood Reporter.
While the "Sweet Child O' Mine" of hitmakers will reunite on the Saturday, Harris, 31, will headline closing night.
Apart from the legends, the festival will also mark the reunion of iconic group LCD Soundsystem, which last played together in 2011.
Other performers at this year's Coachella include Ellie Goulding, Sufjan Stevens, Jack U, Ice Cube, ASAP Rocky, CHVRCHES, Sia, Major Lazer, Flume, Courtney Barnett and Lord Huron.