Similar to their performance last year when they lost nine matches on the trot, Pune suffered their eighth straight loss against Kolkata Knight Riders in their previous game yesterday, when they were beaten by 46 runs.
It would again be a daunting task for Aaron Finch's boys against state rivals Mumbai, who would look to close-in on a play-off berth.
Languishing at the bottom of the table, Pune have won just two of their 13 games, while Mumbai Indians are third in the league table with eight wins in 12 matches.
Only opener Robin Uthappa (31) and all-rounder Angelo Matthews (40) got to double digit figures.
The batting is yet to fire in unison and only the openers have scored some runs at the top. Barring opener Finch's three half-centuries and Uthappa's couple of half-centuries this season, no other Pune batsman, which also includes the likes of Yuvraj Singh, has scored a fifty so far.
Yuvraj has managed just 172 runs from his 10 games, while dangerous batsman Steve Smith has returned to Australia due to a back injury.