The vintage yellow fighter plane crashed at Penmar Golf Course, not far from the Santa Monica airport, Los Angeles Fire Department spokesman Erik Scott said, reported People magazine.
Ford, 72, was the only person on board the craft. An LAPD spokeswoman confirmed the actor is in stable condition.
Ford underwent surgery to repair a broken ankle and pelvis following his death-defying plane crash in California yesterday.
"Harrison was flying a WW2 vintage plane today which had engine trouble upon take off," a representative for Ford said in a statement.
More From This Section
Ford's son Ben, a chef, tweeted on Thursday night that he was at the hospital with his father, who was "battered, but ok! He is every bit the man you would think he is. He is an incredibly strong man. Thank you all for your thoughts and good vibes for my dad."
Santa Monica City Commissioner Phil Brock said the star sustained a head injury.
This is not the first time Ford, an experienced pilot, has been in a plane crash.
His six-passenger plane took a hard landing in Lincoln, Nebraska, in the summer of 2000, but the actor was not hurt. Ford also crash-landed a helicopter in October 1999 while he was practising emergency landings with a flight instructor.
This accident comes month after the actor suffered a broken leg on the set of the upcoming 'Star Wars' movie while shooting in England.