The heatwave, sweeping across the Sindh province, has been going on since the start of Ramzan on Friday, wreaking havoc and triggering an emergency situation in major hospitals of the province.
The death toll in worst-hit Karachi has topped 500 with another eight to 10 people dead in other parts of southern Sindh as a result of soaring temperatures, a senior health official was quoted as saying by media reports.
"We had until yesterday evening nearly 200 deaths from this heatwave," said Seemi Jamali, medical superintendent at Jinnah Hospital.
"These 200 include dead bodies we have got from the scorching heatwave and those who passed away in the hospital while under treatment for heatstroke and dehydration," she said.
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Jamali said the hospital had in four days treated around 3,000 people suffering from illnesses related to the heatwave.
Doctors at the Abbasi Shaheed Hospital said 71 people had died due to the heatwave until yesterday. Saeed Qureshi, a doctor at the Civil hospital, confirmed 70 deaths.
The Pakistan Army and paramilitary Rangers have also set up special centres for treatment of heat stroke victims and also supplied related medicines to government hospitals.
Most of the deaths have occurred due to heat and gastro-related problems, said Salma Kausar, spokesperson Karachi Medical Corporation.
She said 14 women and two children were among those who died yesterday.
Saqib Zeeshan, a spokesman for Indus Hospital, said 20 people had died of heat-related complications at the hospital till yesterday. The Sindh health minister said at least 15 deaths had been registered at Lyari General Hospital.