No one was injured in the incident, the police said.
The incident took place in the morning rush hour when a huge tree in the premises of St Mary's college crashed on a power line snapping it and damaging two vehicles, East Khasi Hills district Deputy Commissioner P S Dkhar said.
A team of the Meghalaya Fire and Emergency Services and forest department officials rushed to the spot to clear the road, he said.
The MeT department has forecast heavy to very heavy rainfall in Meghalaya in the next 24 hours.