Thomas Gilbert was shot in the head at his Beekman Place residence on the East Side yesterday, police said. He was pronounced dead at the scene.
Police were questioning his 30-year-old son, Thomas Gilbert, Jr, today. No charges have been filed.
It was not immediately known if he had a lawyer.
Police said a handgun was found near the body. The elder Gilbert founded Wainscott Capital Partners Fund in 2011.
The fund, which focuses on biotech and health care industries, has USD 200 million in assets.
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Gilbert previously co-founded Syzygy Therapeutics, a biotech asset acquisition fund. He also was founder and CEO of an online teacher-education company called Knowledge Delivery Systems Inc.
He was a graduate of Princeton University and Harvard Business School.
The shooting was a rare act of violence in a tony enclave just north of the United Nations in the Sutton Place neighborhood.