The award was presented by Helen's latest co-star, Ryan Reynolds, who dubbed her the 'Dame of Thrones', reported Daily Telegraph.
The 68-year-old Oscar-winning actress gave an entertaining acceptance speech in which she declared that turning 70 was going to be awesome.
"There are a lot of really young women here who are very beautiful, incredibly talented, and I salute you and respect you all. I'm so proud to be a member of your sex," she said.
"Your 40s are good. Your 50s are great. Your 60s are fab. And 70 is awesome. I'm not quite there yet, but almost," she added.
While presenting Mirren with the Glamour Icon award, Reynolds joked, "For most actors, painstaking preparation involves nothing more than spray tan and a big pile of coke. But this next honoree has shown me that those things just aren't as important as I'd previously thought.