More than 1.6 million cardiovascular-related deaths per year can be attributed to sodium consumption above the World Health Organisation's recommendation of 2.0g (2,000mg) per day, researchers have found.
"High sodium intake is known to increase blood pressure, a major risk factor for cardiovascular diseases including heart disease and stroke," said first and corresponding author Dariush Mozaffarian, dean of the Friedman School of Nutrition Science and Policy at Tufts University.
"However, the effects of excess sodium intake on cardiovascular diseases globally by age, sex, and nation had not been well established," said Mozaffarian, who led the research while at the Harvard School of Public Health.
Effects of sodium on blood pressure and of blood pressure on cardiovascular diseases were determined separately in new pooled meta-analyses, including differences by age and race.
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These findings were combined with current rates of cardiovascular diseases around the world to estimate the numbers of cardiovascular deaths attributable to sodium consumption above 2.0g per day.
The researchers found the average level of global sodium consumption in 2010 to be 3.95g per day, nearly double the 2.0g recommended by the WHO.
The researchers found that reduced sodium intake lowered blood pressure in all adults, with the largest effects identified among older individuals, blacks, and those with pre-existing high blood pressure.
"These 1.65 million deaths represent nearly one in 10 of all deaths from cardiovascular causes worldwide. No world region and few countries were spared," added Mozaffarian.
"We found that four out of five global deaths attributable to higher than recommended sodium intakes occurred in middle- and low-income countries," added John Powles, last author and honorary senior visiting fellow in the department of public health and primary care at the University of Cambridge.