Earnings after taxation surged 146 per cent in the three months to the end of March, from USD 2.58 billion in the same part of 2012, the lender said in a results statement.
Underlying pre-tax profits, stripping out exceptional items, soared 34 per cent to USD 7.6 billion. Revenues rose five percent to USD 17.6 billion.
"We have had a good start to the year, with growth in reported and underlying profit before tax," said chief executive Stuart Gulliver in the earnings release.
"Loan impairment charges were lower in every region, notably in North America," he said, adding that the group was also lifted by its "continued focus on cost management".
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Bad debts -- consumer loans that have turned sour -- sank 44 per cent to USD 1.17 billion in the reporting period. That compared with USD 2.09 billion last time around.
Last year, meanwhile, the bank had posted a 16.5-per cent slump in annual net profits as it was hit by US money-laundering fines, mis-selling scandals, rising taxation and a vast accounting charge.