The finding challenges the previously held view that permanent human occupation of the Tibetan Plateau began no earlier than 5,200 years ago, researchers said.
The new finding is, however, consistent with research on the genetics of modern Tibetan Plateau people showing that they adapted genetically to the high-elevation environment beginning at least 8,000 years ago.
The researchers led by Michael Meyer of the University of Innsbruck in Austria and Mark Aldenderfer of the University of California-Merced in the US conducted an extensive analysis of human handprints and footprints found in 1998 in fossilised hot spring mud near the village of Chusang on Tibet's central plateau, at an elevation of 14,000 feet above sea level.
That still makes the Chusang site the oldest reliably dated archaeological site on the Tibetan Plateau.
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While some have suggested that a human presence on the Tibetan Plateau at those early dates was only a result of short-term, seasonal movement from low-elevation base camps, the new research shows that it is much more likely that the handprints and footprints were made by permanent residents.
The early Tibetan Plateau settlers managed to survive at high elevation at least 7,400 years ago, before the development of an agricultural economy between 5,200-3,600 years ago, researchers said.
"Although an agropastoral lifeway may have enabled substantial population growth after 5,000 years, it by no means was required for the early, likely permanent, occupation of the high central valleys of the Tibetan Plateau," they said.
For example, researchers have been puzzled by the striking differences in how Tibetans and Andean highlanders adapted physiologically to the rigours of life at high elevations, said Randy Haas, a postdoctoral research associate in the University of Wyoming in the US.
"High-elevation environments (over 8,000 feet above sea level) were some of the last places in the world that humans colonised, and so they offer something of a natural laboratory for studying human adaptation," Haas said.
The study was published in the journal Science.