28-year-old Sweeting's personal struggles with painkillers "turned their marriage into nightmare." Cuoco, 29, was allegedly upset that her husband had "developed a dependency on painkillers" to deal with a series of injuries, reported Us Weekly.
"Kaley supported Ryan but she said he couldn't make the commitment to get sober. He'd tell her he was working on it and instead go get wasted," a source said.
The insider added that the actress is "devastated" their marriage has crumbled and has "sworn off dating."
The tennis player had another injury in early 2015 which allegedly caused even more problems.
Cuoco filed for divorce from Sweeting on Friday, September 25, citing the usual "irreconcilable differences.