The women, between 20-24 years old and belonging to Mumbai and Kolkata, had been rescued by Kukatpally Police from the flesh trade four months ago, and lodged at Ujjawala rehabilitation centre here.
They allegedly slipped out early morning today. Police believe that some outsiders were involved in this.
However, other women at the centre alleged that unidentified persons broke in and abducted these women, said the investigating officer.
Local women's organisations protested the incident, demanding more security.