The 49-year-old actor, whose fiance Angelina Jolie recently underwent double mastectomy, raises six kids with her, reported Contactmusic.
"I have very few friends. I have a handful of close friends and I have my family and I haven't known life to be any happier. I'm making things. I just haven't known life to be any happier," he said.
The "Moneyball" star also said he misses his children every time when they are not around.
"I always thought that if I wanted to do a family, I wanted to do it big. I wanted there to be chaos in the house. There's constant chatter in our house, whether it's giggling or screaming or crying or banging. I love it. I hate it when they're gone. I hate it.